In Marsha Rolle’s research laboratory at WPI, teams of graduate and undergraduate students collaborate with researchers at WPI and the University of Massachusetts Medical School to design, fabricate, culture and analyze cell-based engineered vascular tissue. She enjoys collaborating with students to explore the role of cells and ECM on tissue organization and material properties in health and disease, and working with undergraduate student teams to apply engineering principles to design and prototype bioreactors that impart mechanical stimuli on engineered vascular tissues to simulate the hemodynamic environment of the human circulatory system. In the classroom, she frequently relies on her experience as a research scientist in a biomaterials and drug delivery group at a medical device company to educate and excite students about the challenges of bringing cell and molecular therapies from research concept to commercialization and clinical use.