Member Spotlight: Nanostring

NanoString is a leading provider of life science tools for translational research. The company's nCounter®Analysis System has been employed in life science research since 2008 and has been cited in more than 4,000 peer-reviewed publications.

Thanks to engagement with ARMI from its local sales team, NanoString is now part of the BioFabUSA ecosystem. In December of 2020, ARMI began partnering with with the company, providing feedback on the content of a new stem cell characterization panel that was under development. The panel launched in April of 2021, and NanoString joined the ARMI community to partner in further advancing the field of regenerative medicine.

NanoString is a leading provider of life science tools for translational research. The company’s nCounter®Analysis System has been employed in life science research since 2008 and cited in more than 4,000 peer-reviewed publications. The nCounter® Analysis System offers a cost-effective way to easily profile the expression of hundreds of genes, proteins, miRNAs, or copy number variants with high sensitivity and precision, for a variety of research applications including biomarker discovery and validation. The company’s GeoMx® Digital Spatial Profiler enables highly multiplexed spatial profiling of RNA and protein targets in a variety of sample types, including FFPE tissue sections.

The use of stem cells for regenerative medicine is a field that NanoString has been extremely eager to enter. The company has experienced a growing interest in stem cell content and has received numerous requests for a specialized panel that would address the current needs of the field, namely a robust tool for molecular characterization. Expanding into stem cell research is an excellent fit for NanoString as they offer other complementary gene expression panels with synergies in this space. NanoString has been serving the neuroscience community with curated content, and offers a panel focused on metabolism. These panels are excellent tools for measuring bulk gene expression; however, as a leader in the spatial revolution the company is also well positioned to enable exploration of tissue taken from organoids and other regenerative tissues. As a genomic tools provider, they haves a reputation for providing cutting-edge technologies, transparent early technology access programs, and strong collaborative opportunities with global thought leaders. Given the speed with which regenerative medicine is advancing, NanoString is eager to partner with scientists to further expedite developments that improve the human condition.

 Recently the company launched the nCounter® Stem Cell Characterization Panel for deep characterization and optimization of stem cell development. The panel can be used for evaluating viability, confirming functionality, and determining pluripotency within a single workflow that is robust, automated, and reproducible. You can quickly assess stem cell health during production and easily detect contamination, all while getting results in less than 24 hours. The lead designer of the panel at NanoString comes from a stem cell research background and is acutely aware of the challenges surrounding the culturing of these cells. To learn more about his motivation in developing the panel, and how the panel can expedite stem cell research, visit the Brief nCounter stem cell experience.  

 NanoString is extremely excited about the potential of the new Stem Cell Characterization Panel, and is eager to share information on the panel with the ARMI community. Nanostring will be offering product discounts to ARMI members. Throughout the year Nanostring also offers activities and webinars that would be of interest to members. NanoString will be running a global grant program  through June 30th  and would like to invite ARMI members to apply for the chance to receive 24 samples of their choice of either the Human or Mouse nCounter Stem Cell Characterization Panel. Five winners will be chosen globally to receive the grant across all applicants. NanoString is also hosting a free webinar on the stem cell characterization panel that will take place on May 26th and encourages any members who would like to learn more to register.

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BioFabUSA, a program of ARMI, is a public-private partnership with more than 170 members, including companies, academic institutions and not-for profit organizations.

Technology

ARMI

The Advanced Regenerative Manufacturing Institute (ARMI) is a member-based, nonprofit organization whose mission is to advance the bioeconomy of the United States. The institute’s work will positively impact not only manufacturing but also healthcare and education and workforce development in the country.

Commercialization

The Advanced Regenerative Manufacturing Institute (ARMI) is a member-based, nonprofit organization whose mission is to advance the bioeconomy of the United States. The institute’s work will positively impact not only manufacturing but also healthcare and education and workforce development in the country.